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3D-JIGSAW
Automated comparative (homology) protein modelling, including an interactive mode which highlights known domains and allows users to select and align templates.
3D-PSSM Fold Recognition
Combines sequence and structural information for predicting the structure and/or function of your protein sequence, and can detect remote homologies beyond PSI-Blast.
Betapred
Prediction of beta turns and their types using statistical algorithms. 5 different methods including Chou-Fasman, Thornton's PRs, Gorbturn, and a consensus of all methods.
Combinatorial Extension of Polypeptides
Method for finding 3-D similarities in protein structures from the UCSD Supercomputer Center.
EMBL Bioinformatic Harvester
Collection of human (swall) proteins, crossreferences to major prediction servers. Supported predictions from: smart, string, blast, swall, mapview, sosui, ipsort and ncbi conserved domains.
Entelechon Backtranslation tool
Online backtranslation tool for translating a protein sequence into a DNA sequence. The codon usage can be downloaded from a database and adjusted manually for each amino acid, if required. Java applet.
InterPro - The Integrated Resource of Protein Doma
A database built from Pfam, PRINTS and PROSITE.
JAligner
Open source Java implementation of the dynamic programming algorithm Smith-Waterman for biological local pairwise sequence alignment.
Jpred
Secondary protein structure prediction from amino acid sequence; based on a consensus from several methods including DSC, PHD, NNSSP, PREDATOR, ZPRED, and MULPRED.
Molecular Biology Tools Online
Includes WebOligoMelt (Annealing temperature of oligonucleotides), Virtual Ribosome (translate nucleotide sequences into peptides), and SeqScanGraph (graph melting temperature along nucleotide chain).
Munich Information Center for Protein Sequences (M
Bioinformatics research group offering organism specific information (Yeast, Cress) as well as search tools for public databases.
PDB Ligand Environment
Ligand search engine to EBI Macromolecule Structure Database. Provides PDB ID codes with further visualization and statistics charts.
PredictProtein Server
Most widely used server for analysing protein sequences, searching protein databases, and predicting protein structure - from Columbia Univ.
Protein Structure Prediction Server (PSIPRED)
3D protein structure prediction from amino acid sequence. Includes MEMSAT for transmembrane topology prediction, GenTHREADER and mGenTHREADER for fold recognition.
Proteomics Analysis: Z3 and LabOnWeb's Z3OnWe
Proteomic analysis for analyzing 2D-Gel images. Use Compugen's Z3 or Z3OnWeb utitlities for automatic spot detection and registration (=alignment) of protein gel images to match the spots.
Proteomics Tools
Online software for protein analysis from the Swiss Institute of Bioinformatics (SIB).
ProtFun
Ab initio predictions of protein function from protein sequence. The method works by integrating various predicted post-translational and localizational aspects of the proteins submitted.
Protonet
Provides automatic hierarchical classification of proteins sequences.
Quaternary Structure Prediction
An experimental bioinformatics server. Classifies protein sequences as homodimers or non-homodimers. Applications: metabolic reconstruction, protein structure and function assignment, and drug-design.
Swiss-Model
Automated comparative protein modelling server to make protein modelling accessible to biochemists and molecular biologists worldwide - from GlaxoWellcome Experimental Research, Geneva, Switzerland.
Swiss-Pdb Viewer
User-friendly interface allowing analysis of several proteins at once, including superimposition to deduce structural alignments, and compare active sites. From GlaxoWellcome Experimental Research, Geneva, Switzerland.
SWISS-PROT + TrEMBL
The SWISS-PROT database contains high-quality annotation, is non-redundant and cross-referenced to many other databases. SWISS-PROT is accompanied by TrEMBL, a computer-annotated supplement, which contains the translations of all coding sequences (CDS) present in the EMBL Nucleotide Sequence Database, which are not yet integrated into SWISS-PROT.
The Protein Information Resource
In collaboration with the Munich Information Center for Protein Sequences (MIPS) and the Japanese International Protein Sequence Database (JIPID) maintains the PIR-International Protein Sequence Database --- a comprehensive, annotated, and non-redundant set of protein sequence databases in which entries are classified into family groups and alignments of each group are available.